Endocrine Abstracts

Objective: To test the reliability of the classic diabetic survey (DS) in the diagnosis of malnutrition in elderly patients with diabetes mellitus (DM).Patients and Methods: Analytical study of 55 patients aged over 65 years who were hospitalized in the Endocrinology Department. A DS was performed for all patients. The diagnosis of malnutrition was established according to the criteria proposed by the HAS 2021. Two subgroups were compared: G1 (n...

Objective: To determine the influence of metabolic disturbances associated with diabetes mellitus (DM) on the clinical manifestations of the diabetic neurogenic bladder (DNB).Patients and Methods: Analytical cross-sectional study comparing two groups of patients suffering from DM: G1 (n=159) with manifestations of DNB versus G2 (n=41) without signs of DNB.Results: G2 patients were younger than G1 patients (58±1...

Objective: To describe the etiological profile the outcomes of acute pancreatitis (AP) in patients with type 1 diabetes (T1DM).Patients and Methods: A retrospective descriptive study of 10 T1DM patients who presented at least one episode of AP during their follow-up.Results: The mean age at diagnosis of T1DM was 19.7±9.3 years, with a female predominance (60%). T1DM was frequently inaugurated by a cardinal syndrome (50%) or spon...

Introduction: Anemia is defined by the World Health Organization as a hemoglobin concentration less than 120 g/l in women outside of pregnancy, and less than 130 g/l in men over 15 years of age. It is common in diabetics. It can be due to an autoimmune disease associated with type 1 diabetes, whereas the inflammatory cause is the primary cause in type 2 diabetes.Observation: This is a 75 year old patient, type 2 diabetic for 21 years on insulin analogues...

Introduction: Multiple endocrine neoplasia type 1 (MEN1) is a rare autosomal dominant disorder caused by mutations in the MEN1 tumor suppressor gene and is characterized clinically by tumors in two or more endocrine glands, such as the pituitary gland, parathyroid glands or pancreatic islets. We describe an atypical presentation of familial hyperparathyroidism evoking the diagnosis of MEN1 in the first place.Observations: We report a three-member family....

Intoduction: Pitiutary tumor is considered as the first etiology responsable of secondary hypopituitarism. Hypogonadotropic hypogonadism is the most commonly reported lesion.Meterials and methods: It is a retrospective study including 77 cases of prolactinoma. The data collection was done over 17 years, between 2000 and 2017.Results: Gonadotropic deficiency was confirmed in 48 patients (63.6%). A significant negative correlation wa...

Introduction: The non-functional pituitary adenoma (NFPA) is a benign tumor, which has a progressive development but it is a severe tumor by its neuro-ophthalmological and endocrine repercussions.Patients and methods: It is about a descriptive and retrospective study conducted in 35 patients collected in the endocrinology department of Sfax between January 2000 and December 2017. The diagnosis of NFPA was based on the presence of pituitary adenoma on hyp...

Introduction: The simultaneous occurrence in the same patient of more than one endocrinological condition is rare and was described in the multiple endocrine neoplasia (MEN). Here, we report a patient with an unusual combination of primary-hyperparathyroidism, papillary thyroid microcarcinoma, primary-hyperaldosteronism and ACTH-independent Cushing’s syndrome.Case description: A 54-year-old women with a primary-hyperparathyroidism was admitted to ou...

Introduction: Neuroendocrine tumors may develop in almost any organ. These types of tumors may present with giant and asymptomatic mass. We describe a case of a large non functional neuroendocrine tumor reported in the department of endocrinology and diabetology of Hedi Chaker hospital in Sfax-Tunisia in 2016.Presentation of case: A 28 years old male presented with asthenia, gastric heaviness and epigastric pain. Further computerized tomography, a large ...

Introduction: Multiple autoimmune syndrome (MAS) is a rare condition, first described by Humbert and Dupond in 1988 and characterised by three or more autoimmune disorders in the same individual.Case description: Here we present a case of 14-year-old female patient diagnosed with ocular myasthenia gravis. The diagnosis of Graves’ disease was suspected on the basis of hyperthyroidism symptoms and confirmed by undetectable TSH level (<0.01 mUI/l) ...